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Treatment of complex open lower limbs wounds at
           “Instituto Traumatológico”.
              A 30 year experience




                  Dr. Jorge Villegas
                  Servicio de Quemados
                  Hospital de Urgencia Asistencia Pública
                  Instituto Traumatológico
                  Clínica INDISA
                  Santiago. CHILE
                  www.cirugiaplasticayquemados.cl
Wellcome
How did we begin?



1979. Children at Hospital Exequiel Gonzalez Cortes
1980. Victims of employment injuries at“Hospital del Trabajador “

1983. At “ Instituto Traumatológico”


What were our first cases?
What did we learn?


                               ►Osteomyelitis
                               ►Open Fractures
                               ►Degloving
Degloving




Mesh graft
Pigskin heterograft
1979. Osteomyelitis




                           saucering




   Pathological fracture    Design
What did we learn?




►The muscle flaps help
control infection
►The muscle flaps help bone
reparation
►We didn't like the shape
neither the scars of
muslucutaneus flap in legs
1979.- III B open fracture




stabilized with Kirschner wire




                                 External Fixator
The best bone fixation
is necessary


                         Leg saved but shortened
Wound by shotgun pellets
                        Our alternative
                        Soleus. Distal pedicle




1980. Emblematic case
What did we learn?




                     not to use ischemia
Long-term outcome
Where do we work?


 The “Instituto Traumatológico Teodoro Gebauer”
        Old and traditional Hospital
        Founded in 1937,
 Since 1968 It is part of the Chilean Public Health network
What is our Mission?



►Resolve 54 % of the traumatic pathology needs
      of the Metropolitan Area
►12 % of the traumatic pathology needs nation
      wide.
►Teach generations of orthopaedic surgeons
What is our context?

    The “Instituto” keeps some of its old structural characteristics

          ►Focused  on Traumatology
          ►Four operating rooms
          ►No Intensive Care Unit
          ►Small medical staff
          ►No Plastic Surgeon staff
          ►No vascular surgeon staff




            Medical staff composition

          Orthopeadic surgeons          31
          Anesthesiologists             9
          Internist                     1
Why that?

What are our resources?
.


                    Income and per capita health expenditure
    H
    e 4500
    a                                                                                                                        USA

    l 4000
    t 3500
    h
      3000
                                                                                                                     Suiza
    e
      2500                                                                                                 Japon
    x                                                                                          Canadá

    p 2000                                                                                       Francia

    e                                                                                Israel
    n 1500
    d 1000
    i                                                      Argentina
                                                                                España
                                                                                                Singapur

    t 500                     Perú
                                          Chile
                                                  Mexico
    u    0
                                 Brasil


    r
    e      0           5.000               10.000                      15.000        20.000    25.000              30.000      35.000
                                                                           Income Per Capita
Fuente: WHO en US$ PPP 2004
Per capita expenditure on health. OECD Countries

        Estado s Unido s                                                                                  6.401
            Luxemburgo                                                                         5.352
               No ruega                                                             4.364
                   Suiza                                                          4.177
                 A ustria                                                3.519
                 Islandia                                               3.443
                 B élgica                                              3.389
                 Francia                                              3.374
                 Canadá                                               3.326
               A lemania                                             3.287
            A ustralia (2)                                         3.128
             Dinamarca                                            3.108
           Ho landa (1,3)                                         3.094
                  Grecia                                         2.981
                  Irlanda                                       2.926
                  Suecia                                        2.918
OCDE              OCDE                                        2.759
            Reino Unido                                      2.724
                    Italia                                 2.532
               Japó n (1)                               2.358
         Nueva Zelandia                                 2.343
               Finlandia                                2.331
                 España                                2.255
               P o rtugal                           2.033
        República Checa                     1.479
                Hungría                   1.337
                  Co rea                 1.318
             Eslo vaquia               1.137
                P o lo nia          867
                 M éxico          675
Chile               Chile
                 Turquía
                                  668
                                 586

                             0    1.000       2.000         3.000         4.000        5.000      6.000      7.000




                                                                                 Fuente: OECD. Health data 2011
Composition of health expenditures. Public - Private. OECD
             Reino Unido

                   Suecia

                    Japón

                   Francia

                 Finlandia

        Nueva Zelandia

                 Alemania

                        Italia

                  Portugal

                  España

                  Canadá

                    OCDE

                 Australia

                  Holanda

                        Suiza

            Corea del Sur

                        Chile

                   México

       Estados Unidos

                                 0%   10%   20%   30%   40%   50%   60%   70%   80%   90%   100%
  Público     Privado

                                                                     Sourse: OECD. Health data 2007
Chile:
Health Expenditure distribution is
Fifty-fifty Public and Private System
Public Health System serves
         75% of population
Public System Per capita is actually
         about 450 $ US a year
What resources do we have for plastic surgery?



    Plastic Surgery
    ►3 hours for plastic surgery a week




  ►Control
  ►Follow up
  ►Outcome assessment
  Are done by the orthopedic surgeons
What is our experience?



         First Stage.
         1983 to 2000
                 Degloving
                 Osteomyelitis
                 Open Fractures
          Since 2000
          Musculoskeletal tumors surgery was developed
          Complementary or secondary plastic surgery was necessary


       Second Stage
             Degloving
             Osteomyelitis
             Open Fractures
             Muscoloskeletal tumors
What were our goals?


     First Stage

     ►To Select and perform surgical techniques:
       Simple to perform
       Safe
       Short surgical time
       Low morbidity
       Low complications
       High cost-effectiveness
     ►To overcome a vicious circle
It Cannot be repaired because it is infected




It is infected because it is not repaired
What is our protocol?


 Early reparation. Between the 4th and 7th day



 Flaps by segment. Main Indications

►Knee and proximal third of leg: gastrocnemius,

►Medial third: Soleus at proximal pedicle

►Internal Distal third and ankle : Soleus at distal pedicle

►Outer distal third and ankle: reverse fasciocutaneous flap.
Who are our patients?


                  Gender Distribution



                Women
                 31%




                                                Men
                                                69%


                                        Men
                                        Women
Patients with lower limb flaps. 1997 - 2000

Etiology                                        %
Actinic ulcer                                   2
Infected ostheosynthesis                        6
Infected pseudoarthrosis                        2
Open Fractures III B                           73
Chronic Osteomyelitis                           8
Osteosarcoma                                    8
Gunshot Wound                                   2
Total                                          100
Patients distribution according to age
                          30                    27


                          25
                                                           19
Percentage distribution




                          20                                                         16
                                                                                                14
                          15
                                       10
                                                                                                         8
                          10
                                                                         5

                          5


                          0
                                < 20        21 to 30   31 to 40    41 to 50     51 to 60   61 to 70   > 71
                                                                  Age (years)
Pre-existent diseases


                              Yes, 30%




                                         Yes
                                         No




No, 70%
Preexistent diseases

Previous Disease         %
Hypertension             11
Liver Cirrhosis          3
Diabetes Mellitus        5
Alcoholism               5
hypothyroidism           3
Chronic kidney disease   3
                         30
Involved segments


                                                     43
                        45

                        40

                        35
Percentage by segment




                        30

                        25
                                                                    19
                        20                                                    16
                                        14
                        15

                               8
                        10

                         5

                         0
                             Knee   Proximal   Medial third Distal third   Ankle
                                      third
Wound Infection



                       Yes, 57%


                              Yes
                              No




No, 43%
Wound Infection




              5%
        10%

10%                           Staphylococcus aureus
                        47%
                              Pseudomona
                              Proteus
                              Klebsiella
      28%                     Acinetobacter
Why so hight wound infection percentage?

                                             Time before reparation. Porcentage distribution.
                                                                           58%
                                       60%
 Porcentage distribution of patients




                                       50%

                                       40%

                                       30%                   24%


                                       20%
                                                                                                    8%
                                       10%       5%                                         5%


                                       0%
                                              < 10      11 to 30      31 to 90      91 to 180    > 180
                                                            Tíme before reparation (days)
Why the delay in repairing?



      Two reasons:

      ►Workload
      ►Lack of plastic surgeon staff in the emergency service



      Therefore the first surgical toilet is not necessarily
      performed by an expert.
      Therefore it is necessary to repeat the
      procedure more than once.


        During this Period the wound gets infected
What types of flaps do we use?



                   Flaps in lower limbs.

  Flaps
  Muscle flaps                80%
  Fasciocutaneous flaps       20%
Flaps in open Fractures III B


Flaps                            %
Medial gastrocnemius muscle     22
Proximal soleus muscle          40
Distal soleus musle             19
fasciocutaneous                 16
cross-leg flaps                  3
Total                           100
2000. Musculoskeletal tumor surgery



 Emerging issues


   Caused by
   ►the extent of resection
   ►the impact of the radiotherapy
   ►the impact of the chemotherapy
The new issues


   ►Skin defects

   ►Infections

   ►Prosthetics Joints exposure

   ►Allograft bone Exposure




The new goal

      To avoid amputation
Our Goal




     To achieve the greatest therapeutic efficacy with
     the best possible functional aesthetic outcome ,
       minimal complications and the highest cost-
                       effectiveness
What are our criteria for procedure choice



Criteria for procedure choice


  ►Therapeutic efficacy
  ►Quantity and quality of tissue available
  ►Ease of performance
  ► Short surgical time
  ►Security
  ►Low morbidity associated
  ►Cost-effectiveness
Illustrating our experience

cases per segment.
Improving the thigh stump cover   Rectus abdominis
                                  musculocutaneous
                                  flap at distal pedicle
Hip Chondrosarcoma operated
Exposed Prosthesis
Rectus abdominis muscle flap based at distal pedicle
Raised The Flap   passed it through a tunnel
covering the prosthesis
Outcome
covered prosthesis
Allograft bone exposed
Knee
                        Proximal Third of leg




internal gatrocnemius
Muscle flap
Widening the gastrocnemius
               Removing the aponeurosis




Mesh grafted
Exposed Knee
                         External side




External gastrocnemius
Rotated and widened
Mesh Grafted
Exposed Knee prosthesis
                          Reversed adipofacial flap
Short-term result
Middle third
                      Open Fracture
                      Soleus Flap
                      Proximal Pedicle




Without aponeurosis
Soleus sutured to the
tibialis anterior muscle
covering fractured tibia
Exposed
Homograft
Short-term result
Open Fracture and Degloving. Middle and distal third of leg
Soleus
                    Double flap
                    Proximal pedicle and
                    distal pedicle




Long-term outcome
III B Open Fracture Distal Third   Soleus muscle flap distal pedicle
Using only the internal part of distal soleus
using the internal half
Crush Injury
10 days after
Posterior tibial nerve
exposed but viable
Cross-leg fasciocutaneous
reverse flap
Long-term outcome
Tumor resection
Exposed homograft bone
Cross-leg at Distal pedicle
Crush injury . Not apparent degloving
Exposed Heel and
Aquilles region
Covering heel first




Distal Pedicle covers
Aquilles Region
Long-term outcome
repairing the dorsum of the foot
Surgical time and Porcentage distribution


                                   60%                                              53%


                                   50%
Porcentage distribution of cases




                                   40%                       32%


                                   30%


                                   20%
                                                                                                10%


                                   10%        5%



                                   0%
                                         <1              1 to 2              2 to 3        >3
                                                            Surgical time (hours)
Flap Survival

                                                                                            81%
                                      90%
Porcentage distribution of patients




                                      80%
                                      70%
                                      60%
                                      50%
                                      40%
                                      30%
                                                                                   16%
                                      20%
                                             0%         0%             3%
                                      10%
                                      0%
                                            0%    25%              50%           75%     100%
                                                             Flap Survival (%)
Skin Graft take

                                                                                       65%
                                      70%
Porcentage distribution of patients




                                      60%

                                      50%

                                      40%
                                                                               27%
                                      30%

                                      20%

                                             3%                   5%
                                      10%          0%

                                      0%
                                            0%    25%          50%            75%    100%
                                                        Skin Graft take (%)
Complications
                                              63%
                                       70%
POrcenrtage distribution of patients




                                       60%

                                       50%

                                       40%

                                       30%
                                                                           14%                       15%
                                       20%

                                                            3%                           5%
                                       10%

                                       0%
                                             No     Osteomyelitis    Dehiscence     Haematoma   Infection
                                                                    Complications
In summary


       ► The majority of patients were men
       ►Most of them young people without
             preexistent disease.
       ►The most common etiology was open fractures.
       ►More than a half of wounds were infected
►The most frequently compromised segment was the
       middle third
►More than fifty % of wounds were more than 31 days
old at the time of reparation
►The soleus flap was the most used.
•



    ►The majority of cases had no complications.
    ►Our complications were infection and dehiscence.
    ►Flap survival was 100 % in more than 80%
    ►The losses were only marginal.
    ►The long term result was satisfactory in most cases

    ►Surgery time was about two hours.
We achieved the objectives that we wanted to achieve
The Techniques demonstrated their already known
effectiveness.
We managed to avoid amputations




From the point of view of quality care.
The most important problem was the delay in
reparation
The delay facilitates the infection and subsequent
complications
our keys



Strategic Planning
According to our particular resources
Keep in mind Patients’ personal conditions and goals
Not cause additional damage
Anticipate Complications
Keep in mind Cost-effectiveness
Treating Complex Lower Limb Wounds with 30 Years of Experience

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Treating Complex Lower Limb Wounds with 30 Years of Experience

  • 1. Treatment of complex open lower limbs wounds at “Instituto Traumatológico”. A 30 year experience Dr. Jorge Villegas Servicio de Quemados Hospital de Urgencia Asistencia Pública Instituto Traumatológico Clínica INDISA Santiago. CHILE www.cirugiaplasticayquemados.cl
  • 3. How did we begin? 1979. Children at Hospital Exequiel Gonzalez Cortes 1980. Victims of employment injuries at“Hospital del Trabajador “ 1983. At “ Instituto Traumatológico” What were our first cases? What did we learn? ►Osteomyelitis ►Open Fractures ►Degloving
  • 5.
  • 7. 1979. Osteomyelitis saucering Pathological fracture Design
  • 8. What did we learn? ►The muscle flaps help control infection ►The muscle flaps help bone reparation ►We didn't like the shape neither the scars of muslucutaneus flap in legs
  • 9. 1979.- III B open fracture stabilized with Kirschner wire External Fixator
  • 10. The best bone fixation is necessary Leg saved but shortened
  • 11. Wound by shotgun pellets Our alternative Soleus. Distal pedicle 1980. Emblematic case
  • 12. What did we learn? not to use ischemia
  • 14. Where do we work? The “Instituto Traumatológico Teodoro Gebauer” Old and traditional Hospital Founded in 1937, Since 1968 It is part of the Chilean Public Health network
  • 15. What is our Mission? ►Resolve 54 % of the traumatic pathology needs of the Metropolitan Area ►12 % of the traumatic pathology needs nation wide. ►Teach generations of orthopaedic surgeons
  • 16. What is our context? The “Instituto” keeps some of its old structural characteristics ►Focused on Traumatology ►Four operating rooms ►No Intensive Care Unit ►Small medical staff ►No Plastic Surgeon staff ►No vascular surgeon staff Medical staff composition Orthopeadic surgeons 31 Anesthesiologists 9 Internist 1
  • 17. Why that? What are our resources?
  • 18. . Income and per capita health expenditure H e 4500 a USA l 4000 t 3500 h 3000 Suiza e 2500 Japon x Canadá p 2000 Francia e Israel n 1500 d 1000 i Argentina España Singapur t 500 Perú Chile Mexico u 0 Brasil r e 0 5.000 10.000 15.000 20.000 25.000 30.000 35.000 Income Per Capita Fuente: WHO en US$ PPP 2004
  • 19. Per capita expenditure on health. OECD Countries Estado s Unido s 6.401 Luxemburgo 5.352 No ruega 4.364 Suiza 4.177 A ustria 3.519 Islandia 3.443 B élgica 3.389 Francia 3.374 Canadá 3.326 A lemania 3.287 A ustralia (2) 3.128 Dinamarca 3.108 Ho landa (1,3) 3.094 Grecia 2.981 Irlanda 2.926 Suecia 2.918 OCDE OCDE 2.759 Reino Unido 2.724 Italia 2.532 Japó n (1) 2.358 Nueva Zelandia 2.343 Finlandia 2.331 España 2.255 P o rtugal 2.033 República Checa 1.479 Hungría 1.337 Co rea 1.318 Eslo vaquia 1.137 P o lo nia 867 M éxico 675 Chile Chile Turquía 668 586 0 1.000 2.000 3.000 4.000 5.000 6.000 7.000 Fuente: OECD. Health data 2011
  • 20. Composition of health expenditures. Public - Private. OECD Reino Unido Suecia Japón Francia Finlandia Nueva Zelandia Alemania Italia Portugal España Canadá OCDE Australia Holanda Suiza Corea del Sur Chile México Estados Unidos 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Público Privado Sourse: OECD. Health data 2007
  • 21. Chile: Health Expenditure distribution is Fifty-fifty Public and Private System Public Health System serves 75% of population Public System Per capita is actually about 450 $ US a year
  • 22. What resources do we have for plastic surgery? Plastic Surgery ►3 hours for plastic surgery a week ►Control ►Follow up ►Outcome assessment Are done by the orthopedic surgeons
  • 23. What is our experience? First Stage. 1983 to 2000 Degloving Osteomyelitis Open Fractures Since 2000 Musculoskeletal tumors surgery was developed Complementary or secondary plastic surgery was necessary Second Stage Degloving Osteomyelitis Open Fractures Muscoloskeletal tumors
  • 24. What were our goals? First Stage ►To Select and perform surgical techniques: Simple to perform Safe Short surgical time Low morbidity Low complications High cost-effectiveness ►To overcome a vicious circle
  • 25. It Cannot be repaired because it is infected It is infected because it is not repaired
  • 26. What is our protocol? Early reparation. Between the 4th and 7th day Flaps by segment. Main Indications ►Knee and proximal third of leg: gastrocnemius, ►Medial third: Soleus at proximal pedicle ►Internal Distal third and ankle : Soleus at distal pedicle ►Outer distal third and ankle: reverse fasciocutaneous flap.
  • 27. Who are our patients? Gender Distribution Women 31% Men 69% Men Women
  • 28. Patients with lower limb flaps. 1997 - 2000 Etiology % Actinic ulcer 2 Infected ostheosynthesis 6 Infected pseudoarthrosis 2 Open Fractures III B 73 Chronic Osteomyelitis 8 Osteosarcoma 8 Gunshot Wound 2 Total 100
  • 29. Patients distribution according to age 30 27 25 19 Percentage distribution 20 16 14 15 10 8 10 5 5 0 < 20 21 to 30 31 to 40 41 to 50 51 to 60 61 to 70 > 71 Age (years)
  • 30. Pre-existent diseases Yes, 30% Yes No No, 70%
  • 31. Preexistent diseases Previous Disease % Hypertension 11 Liver Cirrhosis 3 Diabetes Mellitus 5 Alcoholism 5 hypothyroidism 3 Chronic kidney disease 3 30
  • 32. Involved segments 43 45 40 35 Percentage by segment 30 25 19 20 16 14 15 8 10 5 0 Knee Proximal Medial third Distal third Ankle third
  • 33. Wound Infection Yes, 57% Yes No No, 43%
  • 34. Wound Infection 5% 10% 10% Staphylococcus aureus 47% Pseudomona Proteus Klebsiella 28% Acinetobacter
  • 35. Why so hight wound infection percentage? Time before reparation. Porcentage distribution. 58% 60% Porcentage distribution of patients 50% 40% 30% 24% 20% 8% 10% 5% 5% 0% < 10 11 to 30 31 to 90 91 to 180 > 180 Tíme before reparation (days)
  • 36. Why the delay in repairing? Two reasons: ►Workload ►Lack of plastic surgeon staff in the emergency service Therefore the first surgical toilet is not necessarily performed by an expert. Therefore it is necessary to repeat the procedure more than once. During this Period the wound gets infected
  • 37. What types of flaps do we use? Flaps in lower limbs. Flaps Muscle flaps 80% Fasciocutaneous flaps 20%
  • 38. Flaps in open Fractures III B Flaps % Medial gastrocnemius muscle 22 Proximal soleus muscle 40 Distal soleus musle 19 fasciocutaneous 16 cross-leg flaps 3 Total 100
  • 39. 2000. Musculoskeletal tumor surgery Emerging issues Caused by ►the extent of resection ►the impact of the radiotherapy ►the impact of the chemotherapy
  • 40. The new issues ►Skin defects ►Infections ►Prosthetics Joints exposure ►Allograft bone Exposure The new goal To avoid amputation
  • 41. Our Goal To achieve the greatest therapeutic efficacy with the best possible functional aesthetic outcome , minimal complications and the highest cost- effectiveness
  • 42. What are our criteria for procedure choice Criteria for procedure choice ►Therapeutic efficacy ►Quantity and quality of tissue available ►Ease of performance ► Short surgical time ►Security ►Low morbidity associated ►Cost-effectiveness
  • 44. Improving the thigh stump cover Rectus abdominis musculocutaneous flap at distal pedicle
  • 46.
  • 47. Rectus abdominis muscle flap based at distal pedicle
  • 48. Raised The Flap passed it through a tunnel
  • 52.
  • 53.
  • 54.
  • 55. Knee Proximal Third of leg internal gatrocnemius Muscle flap
  • 56. Widening the gastrocnemius Removing the aponeurosis Mesh grafted
  • 57. Exposed Knee External side External gastrocnemius Rotated and widened
  • 59.
  • 60.
  • 61. Exposed Knee prosthesis Reversed adipofacial flap
  • 62.
  • 63.
  • 65. Middle third Open Fracture Soleus Flap Proximal Pedicle Without aponeurosis
  • 66. Soleus sutured to the tibialis anterior muscle covering fractured tibia
  • 69. Open Fracture and Degloving. Middle and distal third of leg
  • 70. Soleus Double flap Proximal pedicle and distal pedicle Long-term outcome
  • 71. III B Open Fracture Distal Third Soleus muscle flap distal pedicle
  • 72. Using only the internal part of distal soleus
  • 77.
  • 79. Tumor resection Exposed homograft bone Cross-leg at Distal pedicle
  • 80.
  • 81. Crush injury . Not apparent degloving
  • 83.
  • 84. Covering heel first Distal Pedicle covers Aquilles Region
  • 85.
  • 87. repairing the dorsum of the foot
  • 88. Surgical time and Porcentage distribution 60% 53% 50% Porcentage distribution of cases 40% 32% 30% 20% 10% 10% 5% 0% <1 1 to 2 2 to 3 >3 Surgical time (hours)
  • 89. Flap Survival 81% 90% Porcentage distribution of patients 80% 70% 60% 50% 40% 30% 16% 20% 0% 0% 3% 10% 0% 0% 25% 50% 75% 100% Flap Survival (%)
  • 90. Skin Graft take 65% 70% Porcentage distribution of patients 60% 50% 40% 27% 30% 20% 3% 5% 10% 0% 0% 0% 25% 50% 75% 100% Skin Graft take (%)
  • 91.
  • 92. Complications 63% 70% POrcenrtage distribution of patients 60% 50% 40% 30% 14% 15% 20% 3% 5% 10% 0% No Osteomyelitis Dehiscence Haematoma Infection Complications
  • 93. In summary ► The majority of patients were men ►Most of them young people without preexistent disease. ►The most common etiology was open fractures. ►More than a half of wounds were infected
  • 94. ►The most frequently compromised segment was the middle third ►More than fifty % of wounds were more than 31 days old at the time of reparation ►The soleus flap was the most used.
  • 95. ►The majority of cases had no complications. ►Our complications were infection and dehiscence. ►Flap survival was 100 % in more than 80% ►The losses were only marginal. ►The long term result was satisfactory in most cases ►Surgery time was about two hours.
  • 96. We achieved the objectives that we wanted to achieve The Techniques demonstrated their already known effectiveness. We managed to avoid amputations From the point of view of quality care. The most important problem was the delay in reparation The delay facilitates the infection and subsequent complications
  • 97. our keys Strategic Planning According to our particular resources Keep in mind Patients’ personal conditions and goals Not cause additional damage Anticipate Complications Keep in mind Cost-effectiveness